Known interactions

Accubron Syrup, Accurbron, Acetaminophen and Aspirin and Caffeine powder, Acetaminophen, Aspirin, Caffeine Oral, Acetaminophen, Caffeine, and Dihydrocodeine, Actonel with calcium, Adriamycin, AK-Pred, Alamag, Alamag Suspension, Alenic Alka, AlternaGEL, AlternaGEL Liquid, Alu-Cap, Alu-Tab, Aludrox, Aluminum and Magnesium Hydroxide Oral Suspension, Aluminum and Magnesium Hydroxide, Aluminum Hydroxide, Aluminum Hydroxide and Magnesium Trisilicate, Aluminum Hydroxide Oral Liquid, Aluminum Hydroxide, Magnesium Carbonate Chewables, Aluminum Hydroxide, Magnesium Carbonate Oral Suspension, Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone, Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone oral suspension, Aminophylline (Theophylline) Injection, Aminophylline Tablets, Amitone, Amphojel, Amphojel Suspension, Aquaphyllin, Aquaphyllin Syrup, Ara-C, Asmalix, Asmalix Elixir, Aspirin, Caffeine and Dihydrocodeine, Betaxolol Ophthalmic, Betaxolol Oral, Betoptic, Betoptic S, Bronkodyl, Bumetanide, Bumetanide Injection, Bumex, Bumex Injection, Cafatine PB, Cafatine Suppositories, Cafcit, Cafcit Injection, Cafergot, Cafergot Suppositories, Cafetrate Suppositories, Caffedrine, Caffeine Injection, Caffeine Solution, Caffeine Tablets, Caffeine, Aspirin and Dihydrocodeine, Cal-Citrate, Calcium Acetate, Calcium Acetate Capsules or Gelcaps, Calcium Carbonate Tablets, Calcium Citrate, Calcium chloride, Calcium disodium versenate, Calcium Gluconate, Calcium Lactate, Calcium Salts, Calcium Salts injection, Caltrate 600, Carafate, Carafate Oral Suspension, Cerebyx, Citracal, Citracal Liquitabs, Citrus Calcium, Clozapine, Clozapine Orally-Disentegrating Tablets, Clozaril, Coumadin, Coumadin Injection, CTX, Cyclophosphamide, Cyclophosphamide Injection, Cyclosporine, Cyclosporine Injection, Cyclosporine Ophthalmic, Cyclosporine Oral Solution, Cytarabine, Cytosar-U, Cytoxan, Cytoxan Injection, Daunorubicin Liposomal Injection, DaunoXome, DDI, Demadex Injection, Demadex Oral, Di-Gel, Dialume, Diastat, Diazepam, Diazepam Injection, Diazepam Intensol, Diazepam Oral Solution, Diazepam Rectal Gel, Dicarbosil, Didanosine, Didanosine Delayed Release Capsule, Didanosine Pediatric Oral Solution, Didanosine Powder for Oral Solution, Dihydrocodeine, Aspirin and Caffeine, Dilantin, Dilantin Infatab, Dilantin Injection, Dilantin Kapseals, Dilantin-125, Dolophine, Dolophine Oral, Dolophine Oral Solution, Doxorubicin, Econopred, Econopred Plus, Edecrin, Elixomin, Elixomin Elixir, Elixophyllin, Elixophyllin Elixir, Enerjets, Equilet, Ercaf, Ergo-Caff, Ergotamine and Caffeine Rectal Suppositories, Ergotamine Tartrate and Caffeine, Ethacrynic Acid, Excedrin Extra Strength, Excedrin Migraine, Fazoclo, Fe-Tinic, Ferrex 150, Fluoxetine and Olanzapine, Foscarnet Sodium Injection, Foscavir, Fosphenytoin, Furosemide, Furosemide Injection, Furosemide Oral Solution, Gaviscon, Gaviscon Chewable, Gaviscon Chewable Tablets, Gengraf, Gengraf Solution, Goody's Extra Strength Headache Powder, Inderal, Inderal IV, Inflamase Forte, Inflamase Mild, Iosopan, Jantoven, Kerlone Oral, Lanophyllin, Lanophyllin Elixir, Lasix, Lasix Injection, Lasix Oral Solution, Lopressor, Lopressor HCT, Lopressor Injection, Maalox, Maalox Suspension, Magaldrate, Magnalox, Magnalox Suspension, Magnesium Hydroxide, Magnesium Hydroxide Chewable Tablets, Magnox Suspension, Mallamint, Methadone Diskets, Methadone Dispersible, Methadone hydrochloride injection, Methadone Injection, Methadone Oral, Methadone Oral Solution, Methadose, Metoprolol and Hydrochlorothiazide, Metoprolol ER, Metoprolol Injection, Metoprolol Oral, Mexiletine, Mexitil, Migergot, Milk of Magnesia, Milk of Magnesia-Concentrated, Mintox Suspension, Mitoxantrone, Mylanta, Mylanta Oral Suspension, Mylanta tablets, Neocaf Injection, Neoral, Neoral Injection, Neoral Solution, Neosar, Niferex, Niferex 150, NoDoz, Novantrone, Nu-Iron, Nu-Iron-150, Olanzapine, Olanzapine Disintegrating Tablets, Olanzapine Injection, Oncovin, Orapred, Panlor DC, Panlor SS, Pediapred, Phenytek, Phenytoin, Phenytoin Chewable, Phenytoin Injection, Phenytoin Oral Suspension, Phillips Milk of Magnesia, Phillips' Chewable, PhosLo, Phoslo Capsules, Phoslo Gelcaps, Polysaccharide Iron Complex, Polysaccharide Iron Complex Elixir, Posture, Pred Forte, Pred Mild, Prednisolone Injection, Prednisolone Liquid, Prednisolone Ophthalmic, Prednisolone Tablets, Prelone, Procainamide ER, Procainamide Injection, Procainamide Oral, Procan SR, Procanbid, Pronestyl, Pronestyl Injection, Pronestyl-SR, Propranolol, Propranolol Injection, Propranolol Oral Solution, Quibron-T Dividose, Quibron-T/SR Dividose, Renagel, Respbid, Restasis, Riopan, Risedronate with calcium carbonate, Rubex, Rulox, Sandimmune, Sandimmune Injection, Sandimmune Solution, Sevelamer, Slo-bid Gyrocaps, Slo-Phyllin, Slo-Phyllin Gyrocaps, Slo-Phyllin Syrup, Sucralfate, Sucralfate Oral Suspension, Sustaire, Symbyax, Synalgos-DC, T-Phyl, Theo-24, Theo-Dur, Theo-Sav, Theo-X, Theobid Duracaps, Theochron, Theoclear L.A., Theoclear-80, Theoclear-80 Syrup, Theolair, Theolair Injection, Theolair Solution, Theolair SR, Theophylline ER, Theophylline Injection, Theophylline Oral Solution, Syrup, or Suspension, Theophylline Tablets or Capsules, Theospan-SR, Theostat 80, Theostat-80 Syrup, Theovent, Titralac, Tizanidine, Toprol XL, Torsemide Injection, Torsemide Oral, Tricalcium Phosphate, Tums, Uni-Dur, Uniphyl, Valium, Valium Injection, Vanquish, Videx, Videx EC, Videx Pediatric Oral Solution, Videx Powder for Oral Solution, Vincasar, Vincristine, Vivarin, Warfarin, Warfarin injection, Wigraine, Wigraine Suppositories, Zanaflex, Zyprexa, Zyprexa Injection, Zyprexa Zydis, Zyprexa Zydis Injection, Food and alcohol.

Quick guide to Cipro

Brand Name(s): Cipro

Generic Name Ciprofloxacin tablets

What are ciprofloxacin tablets?

CIPROFLOXACIN (Cipro®) is an antibiotic. This drug treats many kinds of infections of the skin, bone, stomach, brain, blood, lungs, ear, and urinary tract. It also treats certain sexually transmitted diseases. Generic ciprofloxacin tablets are available.

What should my health care professional know before I take ciprofloxacin?

They need to know if you have any of these conditions:

  • dehydration
  • kidney disease
  • liver disease
  • seizures (convulsions)
  • stomach problems (especially colitis)
  • an unusual or allergic reaction to ciprofloxacin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I take this medicine?

Take tablets by mouth. Follow the directions on the prescription label. Swallow ciprofloxacin tablets whole with a full glass of water. Although this medicine can be taken with meals, it is best to take ciprofloxacin on an empty stomach. One hour before or two hours after meals is the preferred time. Do not take with magnesium/aluminum antacids, sucralfate, Videx® (didanosine) chewable/buffered tablets or pediatric powder, or with other products containing calcium, iron or zinc. Ciprofloxacin may be taken two hours before or six hours after taking these products. Ciprofloxacin should not be taken with dairy products (such as milk or yogurt) or calcium-fortified juices alone; however, ciprofloxacin may be taken with a meal that contains these products. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. This medication should be taken at regular intervals.

What drug(s) may interact with ciprofloxacin?

  • acetazolamide
  • aluminum salts
  • antacids
  • caffeine
  • calcium salts
  • citric acid; potassium citrate; sodium citrate products
  • didanosine, ddI
  • iron supplements
  • magnesium salts
  • manganese
  • medicines for diabetes
  • methazolamide
  • multivitamins containing calcium, iron, magnesium, manganese, or zinc
  • mexiletine
  • NSAIDs such as Advil®, Aleve®, ibuprofen, Motrin®, naproxen
  • phenytoin
  • probenecid
  • sodium bicarbonate
  • sucralfate
  • theophylline
  • ursodiol
  • warfarin
  • zinc salts

Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking ciprofloxacin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • difficulty breathing
  • fever
  • hallucinations
  • increased sensitivity to the sun or ultraviolet light
  • irregular heartbeat, palpitations or chest pain
  • joint, muscle or tendon pain
  • nervousness, excitability, restlessness
  • reduced amount of urine
  • severe or watery diarrhea
  • skin rash, itching
  • seizures (convulsions)
  • swelling of the face or neck
  • unusual pain, numbness, tingling, or weakness
  • vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • diarrhea
  • difficulty sleeping
  • dizziness, drowsiness
  • headache
  • nausea
  • stomach upset

What should I watch for while taking ciprofloxacin?

Tell your prescriber or health care professional if your symptoms do not improve in 2 to 3 days.

If you get severe or watery diarrhea, do not treat yourself. Call your prescriber or health care professional for advice.

Make sure you stay well hydrated while taking ciprofloxacin. Drink several glasses of water a day. This helps to prevent crystals of the drug from developing in your urine.

Cut down on drinks that contain caffeine. Ciprofloxacin can increase the stimulant effects of caffeine and cause heart, breathing and other problems.

Keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or sun tanning beds or booths.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how ciprofloxacin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient.

Antacids can make ciprofloxacin ineffective. If you get an upset stomach and want to take an antacid, make sure there is an interval of at least 2 hours since you last took ciprofloxacin, or 6 hours before your next dose. Iron and zinc preparations can also make ciprofloxacin ineffective. Do not take multivitamins at the same time you take your ciprofloxacin tablets.

If you notice pain or swelling of a tendon or around a joint, stop taking ciprofloxacin. Call your healthcare provider. Rest the affected area. Do not exercise or take ciprofloxacin until your healthcare provider tells you to do so.

If you notice pain, burning, tingling, numbness and/or weakness, discontinue ciprofloxacin and call your healthcare professional immediately.

Stop taking ciprofloxacin if you develop a skin rash or other allergic reaction. Call your healthcare provider immediately.

If you are going to have surgery, tell your prescriber or health care professional that you are taking ciprofloxacin.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature below 30 °C (86 °F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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