Known interactions

Acephen Suppositories, Acetaminophen, Acetaminophen and Aspirin and Caffeine powder, Acetaminophen and Butalbital, Acetaminophen and Pseudoephedrine, Acetaminophen Oral Suspension or Syrup, Acetaminophen Suppositories, Acetaminophen, Aspirin, Caffeine Oral, Acetaminophen, Caffeine, and Dihydrocodeine, Actoplus Met, Aldactazide, Alka-Seltzer Plus Cold and Sinus, Amantadine, Amantadine Oral Syrup, Amiloride and Hydrochlorothiazide, Aquatensen, Aspirin Free Anacin, Atenolol, Atenolol and Chlorthalidone, Atenolol Injection, Avandamet, Axocet, Benicar HCT, Bucet, Bupap, Butex Forte, Carbidopa, Levodopa, Entacapone, Cephadyn, Chinese Club Moss, Chlorothiazide, Chlorothiazide Injection, Chlorothiazide Suspension, Chlorpromazine, Chlorpromazine Concentrate or Syrup, Chlorpromazine Extended-Release Capsules, Chlorpromazine Injection, Chlorpromazine Intensol Concentrate, Chlorpromazine Suppositories, Chlorthalidone, Cimetidine, Cimetidine Injection, Cimetidine Liquid, Compazine, Compazine Injection, Compazine Rectal Suppositories, Compazine Spansules, Compazine Syrup, Corzide, Datril, Digitek, Digoxin, Digoxin Injection, Digoxin Liquid, Diurigen, Diuril, Diuril Injection, Diuril Suspension, Dolgic, Dopar, Duradrin, Dyazide, Enduron, Esidrix, Etrafon, Excedrin Extra Strength, Excedrin Migraine, Ezide, Feverall Suppositories, Fluphenazine, Fluphenazine Injection, Fluphenazine Oral Concentrate or Elixir, Fortamet, Furadantin, Genapap, Genapap Children, Genebs, Glipizide and Metformin, Glucophage, Glucophage XR, Glucovance, Glyburide and Metformin, Goody's Extra Strength Headache Powder, Haldol Decanoate Injection, Haldol Injection, Haldol Oral Concentrate, Haldol Tablets, Haloperidol Decanoate Injection, Haloperidol Lactate Injection, Haloperidol Oral Concentrate, Haloperidol Tablets, Hup A, Huperzia serrata, Huperzine A, Hydrochlorothiazide, HydroDIURIL, Hygroton, Indapamide, Infantaire, Isometheptene Mucate, Dichloralphenazone, and Acetaminophen, Lanoxicaps, Lanoxin, Lanoxin Injection, Lanoxin Liquid, Larodopa, Levodopa, Liquiprin, Lisinopril and Hydrochlorothiazide, Lopressor HCT, Lozol, Lycopodium serrata, Macrobid, Macrodantin, Mapap Children's, Mapap Sinus, Maxzide, Mellaril, Mellaril Suspension, Mellaril-S, Meperidine and Promethazine Oral, Meprozine, Mesoridazine Injection, Mesoridazine Oral, Mesoridazine Oral Concentrate, Metaglip, Metformin, Metformin Extended-Release, Metformin Oral Solution, Methyclothiazide, Metolazone, Metolazone extended-release tablets, Metoprolol and Hydrochlorothiazide, Microzide, Midchlor, Midrin, Migratine, Mitride, Moduretic, Mykrox, Nadolol and Bendroflumethiazide, Neopap Suppositories, Nitrofurantoin, Nitrofurantoin Oral Suspension, Olmesartan and Hydrochlorothiazide, Oretic, Ornex, Panadol, Panadol Infants, Panlor DC, Panlor SS, Permitil, Permitil Oral Concentrate, Perphenazine and Amitriptyline, Perphenazine Injection, Perphenazine Oral, Perphenazine Oral Concentrate, Phenergan, Phenergan and Codeine, Phenergan DM, Phenergan Injection, Phenergan Rectal Suppositories, Phenergan Syrup, Phenergan VC, Phenergan VC with Codeine, Phenylephrine, Promethazine and Codeine, Pherazine VC, Phrenilin Forte, Pioglitazone and Metformin, Prinzide, Prochlorperazine, Prochlorperazine ER, Prochlorperazine Injection, Prochlorperazine Oral Syrup, Prochlorperazine Rectal Suppositories, Prolixin, Prolixin Decanoate, Prolixin Elixir, Prolixin Enanthate, Prolixin Injection, Prolixin Oral Concentrate, Prometh and Codeine, Prometh VC Plain, Prometh with Dextromethorphan, Promethazine and Codeine, Promethazine and Dextromethorphan, Promethazine and Phenylephrine, Promethazine DM, Promethazine Injection, Promethazine Oral, Promethazine Oral Syrup, Promethazine Rectal Suppositories, Promethazine VC with Codeine, Promethegan, Qian Ceng Ta, Repan CF, Riomet, Rosiglitazone and Metformin, Sedapap, Serentil, Serentil Injection, Serentil Oral Concetrate, Shuangyiping, Sonazine Concentrate, Sonazine Syrup, Spironolactone and Hydrochlorothiazide, Stalevo, Stelazine, Stelazine Injection, Sudafed Sinus and Cold, Sudafed Sinus Headache, Symadine, Symmetrel, Symmetrel Oral Syrup, Tagamet, Tagamet HB, Tagamet Injection, Tagamet Liquid, Tempra, Tencon, Tenoretic, Tenormin, Tenormin Injection, Thalitone, Thiethylperazine Injection, Thiethylperazine Oral, Thiethylperazine Suppositories, Thioridazine Suspension, Thioridazine Tablets, Thor-Prom, Thorazine, Thorazine Concentrate, Thorazine Injection, Thorazine Spansule, Thorazine Suppositories, Thorazine Syrup, Torecan Injection, Torecan Oral, Tramadol and Acetaminophen, Triamterene and Hydrochlorothiazide, Triavil, Trifluoperazine Injection, Trifluoperazine Oral Concentrate, Trifluoperazine Oral Tablets, Trilafon, Trilafon Concentrate, Trilafon Injection, Tylenol, Tylenol Liquid, Tylenol Sinus, Ultracet, Valorin, Vanquish, Zaroxolyn, Zestoretic.

Introduction into Gastrosed

Brand Name(s): Anaspaz, Cystospaz, Cystospaz-M, Donnamar, ED-SPAZ, Gastrosed, Levsin, Levsinex Timecaps, Neosol, Symax-SL, Symax-SR

Generic Name Hyoscyamine

What are hyoscyamine tablets or capsules?

HYOSCYAMINE (Anaspaz®, Cystospaz®, Gastrosed®, Levbid®, Levsin®, Levsin/SL®, Levsinex®) treats different bowel problems including irritable bowel syndrome. Generic hyoscyamine capsules and tablets are available.

What should my health care professional know before I take hyoscyamine?

They need to know if you have any of these conditions:

  • closed-angle glaucoma
  • diarrhea
  • difficulty passing urine
  • heart disease, or previous heart attack
  • hiatal hernia
  • myasthenia gravis
  • prostate trouble
  • stomach infection
  • stomach obstruction
  • ulcerative colitis
  • an unusual or allergic reaction to hyoscyamine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I take this medicine?

Take hyoscyamine tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take the tablets 30 to 60 minutes before food. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with hyoscyamine?

  • amantadine
  • benztropine
  • cisapride
  • digoxin
  • donepezil
  • galantamine
  • medicines for heart problems
  • medicines for hay fever and other allergies
  • medicines for mental problems or psychotic disturbances
  • opiate prescription pain medications such as codeine, hydromorphone, and morphine
  • potassium salts
  • quinidine
  • rivastigmine
  • tacrine
  • tegaserod

Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking hyoscyamine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • anxiety, nervousness
  • blurred vision or other eye problems
  • confusion
  • dizziness or fainting spells
  • fast heartbeat
  • fever
  • pain or difficulty passing urine
  • unusual weakness or tiredness
  • vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • altered taste
  • constipation
  • drowsiness
  • dry mouth
  • increased sensitivity of the eyes to sun or ultraviolet light
  • nausea

What should I watch for while taking hyoscyamine?

You may get dizzy or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how hyoscyamine affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, avoid alcoholic drinks.

Stay out of bright light and wear sunglasses if hyoscyamine makes your eyes more sensitive to light.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.

Hyoscyamine may cause dry eyes and blurred vision. If you wear contact lenses, you may feel some discomfort. Lubricating drops may help. See your ophthalmologist if the problem does not go away or is severe.

Avoid extreme heat (e.g., hot tubs, saunas). Hyoscyamine can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 °C (59 and 86 °F). Throw away any unused medicine after the expiration date.

(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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