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Introduction into Haldol Decanoate Injection

Brand Name(s): Haldol Decanoate Injection

Generic Name Haloperidol Decanoate Injection

What is haloperidol long-acting injection?

HALOPERIDOL (Haldol® Decanoate) helps to treat schizophrenia. Haloperidol can help you to keep in touch with reality and reduce your mental problems. Generic haloperidol long-acting injections are not yet available.

What should my health care professional know before I receive haloperidol?

They need to know if you have any of these conditions:

  • blood disease
  • breast cancer
  • difficulty passing urine
  • glaucoma
  • head injury
  • heart disease
  • low blood calcium
  • lung disease
  • over-active thyroid
  • Parkinson's disease
  • prostate trouble
  • seizures (convulsions)
  • tobacco smoker
  • an unusual or allergic reaction to haloperidol, tartrazine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Haloperidol is for injection into a muscle. It is given by a health-care professional. The long-acting form of haloperidol should only be used when you have already been stabilized on other short-acting haloperidol. Most patients receive one injection a month, but the dose must be determined for each individual.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

Elderly patients over age 65 years may have a stronger reaction to this medicine and need smaller doses.

What if I miss a dose?

Try not to miss a dose. If you are unable to keep an appointment, call your prescriber or health care professional to reschedule.

What drug(s) may interact with haloperidol?

  • alcohol
  • atropine
  • barbiturate medicines for inducing sleep or treating seizures (convulsions)
  • benztropine
  • cabergoline
  • carbamazepine
  • dicyclomine
  • dopamine
  • epinephrine
  • levodopa or other medicines for Parkinson's disease
  • lithium
  • medicines for hay fever and other allergies
  • medicines for fungal infections
  • medicines for high blood pressure
  • medicines for pain
  • medicines to control heart rate
  • other medicines for mental problems, like mental depression
  • rifampin
  • water pills

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from receiving haloperidol?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • confusion
  • difficulty breathing
  • difficulty in speaking or swallowing
  • difficulty passing urine, or sudden loss of bladder control
  • dizziness or lightheadedness
  • fast or irregular heartbeat (palpitations)
  • fever, chills, or sore throat
  • hot, dry skin or lack of sweating
  • loss of balance or difficulty walking
  • seizures (convulsions)
  • stiffness, spasms, trembling
  • uncontrollable tongue or chewing movements, smacking lips or puffing cheeks
  • uncontrollable muscle spasms, in the face hands, arms, or legs, twisting body movements
  • unusual weakness or tiredness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • anxiety or agitation
  • blurred vision
  • breast pain or swelling
  • constipation
  • decreased sexual ability
  • drowsiness
  • dry mouth
  • increased sensitivity to the sun (severe sunburn)
  • menstrual changes
  • nausea or vomiting
  • pain or irritation at the injection site
  • skin rash
  • unusual production of breast milk
  • weight gain

What should I watch for while taking haloperidol?

Remember that the effects of long-acting haloperidol can be seen for up to six weeks. Information on precautions and side effects apply during this time.

You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how haloperidol affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase dizziness and drowsiness. Avoid alcoholic drinks. You can get a hangover effect the morning after a bedtime dose.

Do not treat yourself for colds, diarrhea or allergies. Ask your prescriber or health care professional for advice, some nonprescription medicines may increase possible side effects.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help. Be careful when brushing and flossing your teeth to avoid mouth infections or damage to your gums. See your dentist regularly.

If you are going to have surgery tell your prescriber or health care professional that you are taking haloperidol.

Avoid extreme heat or cold. Haloperidol can stop you sweating and increase your body temperature. It can also make your body unable to stand extreme cold. Avoid hot baths and saunas. Be careful about exercising especially in hot weather. Dress warmly in cold weather and do not stay out long in the cold.

Haloperidol may make you more sensitive to sun or ultraviolet light. Keep out of the sun, or wear protective clothing outdoors and use a sunscreen (at least SPF 15). Do not use sun lamps, or sun tanning beds or booths. To protect your eyes wear sunglasses even on cloudy days.

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 °C (59 and 86 °F); do not refrigerate or freeze. Protect from light. Throw away any unused medicine after the expiration date.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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