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Known interactions

Acebutolol, Activated Charcoal, Actonel, Actonel with calcium, AKTob, Aldactazide, Alendronate and cholecalciferol, Alendronate Oral Solution, Alendronate tablets, Alendronate weekly tablets, Amethopterin, Amikacin Sulfate Injection, Amikin, Amiloride and Hydrochlorothiazide, Anafranil, Aquatensen, Aredia, Aspirin and Carisoprodol, Aspirin, Caffeine and Dihydrocodeine, Atenolol, Atenolol and Chlorthalidone, Atenolol Injection, Axid AR, Axid Capsules, Axid Oral Solution, Baclofen Injection, Baclofen Oral, Benemid, Benicar HCT, Betapace, Betapace AF, Betaxolol Ophthalmic, Betaxolol Oral, Betimol, Betoptic, Betoptic S, Bisoprolol, Blocadren, Brevibloc, Buffered Aspirin and Pravastatin, Bumetanide, Bumetanide Injection, Bumex, Bumex Injection, Caffeine, Aspirin and Dihydrocodeine, Carisoprodol Compound, Carteolol, Carteolol Ophthalmic, Cartrol, Celexa, Celexa Solution, Cerebyx, CharcoAid, Charcoal, Charcoal capsules, Charcoal Plus, Charcoal powder or oral suspension, CharcoCaps, Chlorothiazide, Chlorothiazide Injection, Chlorothiazide Suspension, Chlorthalidone, Chroma-Pak injection, Chromic Chloride injection, Chromium, Chromium 3, Chromium Acetate, Chromium Chloride, Chromium chloride injection, Chromium injection, Chromium Picolinate, Cimetidine, Cimetidine Injection, Cimetidine Liquid, Citalopram, Citalopram Oral Solution, Citalopram orally-disintegrating tablets, Clomipramine, Cognex, Corgard, Corzide, Cosopt, Coumadin, Coumadin Injection, Creatine, Creatine Citrate, Creatine Monohydrate, Creatine Phosphate, Cyclosporine, Cyclosporine Injection, Cyclosporine Ophthalmic, Cyclosporine Oral Solution, citalopram orally-disintegrating tablets, Defy, Demadex Injection, Demadex Oral, Desipramine, Didronel, Didronel Injection, Digitek, Digoxin, Digoxin Injection, Digoxin Liquid, Dihydrocodeine, Aspirin and Caffeine, Dilantin, Dilantin Infatab, Dilantin Injection, Dilantin Kapseals, Dilantin-125, Diurigen, Diuril, Diuril Injection, Diuril Suspension, Dorzolamide and Timolol Ophthalmic, Dyazide, Dyrenium, Edecrin, Enduron, Escitalopram, Escitalopram Oral Solution, Esidrix, Eskalith, Eskalith CR, Esmolol, Ethacrynic Acid, Etidronate Disodium, Etidronate Disodium Injection, Ezide, Famotidine, Famotidine Injection, Famotidine Oral Suspension, FK 506, Fluoxetine and Olanzapine, Fluoxetine capsules (Sarafem), Fluoxetine Oral Solution, Fluoxetine tablets or capsules, Fluvoxamine, Fosamax, Fosamax 35, Fosamax 70, Fosamax Oral Solution, Fosamax Plus D, Fosphenytoin, Furosemide, Furosemide Injection, Furosemide Oral Solution, fluoxetine delayed-release capsules, Garamycin Cream, Garamycin Injection, Garamycin Opthalmic, Gengraf, Gengraf Solution, Genoptic, Gentacidin, Gentafair, Gentak, Gentamicin Ophthalmic Drops or Ointment, Gentamicin Sulfate Injection, Gentamicin Topical, Ginkgo, Ginkgo Biloba, Hydrochlorothiazide, HydroDIURIL, Hygroton, Indapamide, Inderal, Inderal IV, Jantoven, Japanese Silver Apricot, Jenamicin Injection, Kerlone Oral, Kew Tree, Lanoxicaps, Lanoxin, Lanoxin Injection, Lanoxin Liquid, Lasix, Lasix Injection, Lasix Oral Solution, Latanoprost; Timolol eye solution, Levatol, Lexapro, Lexapro Oral Solution, Lioresal, Lioresal Injection, Lisinopril and Hydrochlorothiazide, Lithane, Lithium, Lithium Oral Syrup, Lithium, Extended-Release, Lithobid, Lithonate, Lithotabs, Lopressor, Lopressor HCT, Lopressor Injection, Lozol, Luvox, Maidenhair Tree, Maxzide, Methotrexate, Methotrexate Injection, Methyclothiazide, Metolazone, Metolazone extended-release tablets, Metoprolol and Hydrochlorothiazide, Metoprolol ER, Metoprolol Injection, Metoprolol Oral, Microzide, Moduretic, MTX Injection, Mykrox, Nadolol, Nadolol and Bendroflumethiazide, Nebcin, Neoral, Neoral Injection, Neoral Solution, Nizatadine Capsules, Nizatadine Oral Solution, Norpramin, Ocu-Mycin, Ocupress, Olmesartan and Hydrochlorothiazide, Oretic, Pamidronate Injection, Paroxetine, Paroxetine Oral Suspension, Paxil, Paxil CR, Paxil Suspension, Penbutolol, Pepcid AC, Pepcid Injection, Pepcid Oral, Pepcid Oral Suspension, Phenytek, Phenytoin, Phenytoin Chewable, Phenytoin Injection, Phenytoin Oral Suspension, Pindolol, Pravigard PAC, Prinzide, Probalan, Probenecid, Prograf, Prograf Injection, Propranolol, Propranolol Injection, Propranolol Oral Solution, Protopic, Prozac, Prozac Oral Solution, Prozac Weekly, Ranitidine, Ranitidine Effervescent Tablets or Granules, Ranitidine Hydrochloride Injection, Ranitidine Oral Syrup, Restasis, Rheumatrex, Risedronate, Risedronate with calcium carbonate, Sandimmune, Sandimmune Injection, Sandimmune Solution, Sarafem, Sectral, Sertraline, Sertraline Oral Solution, Skelid, Sodol Compound, Soma Compound, Sotalol, Spironolactone and Hydrochlorothiazide, Streptomycin, Symbyax, Synalgos-DC, Tacrine, Tacrolimus, Tacrolimus Injection, Tacrolimus ointment, Tagamet, Tagamet HB, Tagamet Injection, Tagamet Liquid, Tenoretic, Tenormin, Tenormin Injection, Thalitone, Tiludronate, Timolol Ophthalmic, Timolol Oral, Timoptic, Timoptic-XE, TOBI, TobraDex, Tobramycin and Dexamethasone Ophthalmic, Tobramycin Inhalation Solution, Tobramycin Ophthalmic Drops, Tobramycin Ophthalmic Ointment, Tobramycin Sulfate Injection, Tobrex Eye Drops, Tobrex Eye Ointment, Toprol XL, Torsemide Injection, Torsemide Oral, Trexall, Triamterene, Triamterene and Hydrochlorothiazide, Trivalent Chromium, Vantage, Visken, Warfarin, Warfarin injection, Xalcom, Yinhsing, Zantac, Zantac 75, Zantac EFFERdose, Zantac Injection, Zantac Syrup, Zaroxolyn, Zebeta, Zestoretic, Zoloft, Zoloft Oral Solution.

Introduction into Haltran

Brand Name(s): Advil, Advil Liqui-Gels, Advil Migraine, Genpril, Haltran, Junior Strength Advil, Junior Strength Motrin, Menadol, Midol Maximum Strength Cramp Formula, Motrin, Motrin IB, Motrin Migrain Pain, Nuprin, Rufen

Generic Name Ibuprofen

What are ibuprofen tablets or caplets?

IBUPROFEN (Motrin®, Advil®, Rufen®, Nuprin®) is an antiinflammatory drug. Ibuprofen reduces inflammation and eases mild to moderate pain. It reduces fever and relieves the symptoms of rheumatoid arthritis (rheumatism), osteoarthritis, menstrual cramps or premenstrual pain and swelling. Generic ibuprofen tablets and caplets are available.

What should my health care professional know before I take ibuprofen?

They need to know if you have any of these conditions:

  • anemia
  • asthma, especially aspirin sensitive asthma
  • bleeding problems or taking medicines that make you bleed easily such as anticoagulants ('blood thinners')
  • cigarette smoker
  • diabetes
  • drink more than 3 alcohol-containing beverages a day
  • heart failure
  • high blood pressure
  • kidney disease
  • liver disease
  • stomach or duodenal ulcers
  • systemic lupus erythematosus
  • ulcerative colitis
  • an unusual or allergic reaction to aspirin, other salicylates, other NSAIDs, other medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I take this medicine?

Take ibuprofen tablets or caplets by mouth. Follow the directions on the label. Swallow tablets whole with a full glass of water; take tablets in an upright or sitting position. Taking a sip of water first, before taking the tablets, may help you swallow them. If possible take bedtime doses at least 10 minutes before lying down. Ibuprofen may be taken with food if it upsets your stomach. Take your doses at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with Ibuprofen?

  • alcohol
  • anti-inflammatory drugs (other NSAIDs, prednisone)
  • aspirin and aspirin-like medicines
  • cidofovir
  • cyclosporine
  • entecavir
  • herbal products that contain feverfew, garlic, ginger, or ginkgo biloba
  • lithium
  • medicines for high blood pressure
  • medicines that affect platelets
  • medicines that treat or prevent blood clots such as warfarin and other 'blood thinners'
  • methotrexate
  • pemetrexed
  • water pills (diuretics)

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking ibuprofen?

Elderly patients are at increased risk for developing side effects.

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • signs of bleeding - bruising, pinpoint red spots on the skin, black tarry stools, blood in the urine, unusual tiredness or weakness
  • signs of an allergic reaction - difficulty breathing or wheezing, skin rash, redness, blistering or peeling skin, hives, or itching, swelling of eyelids, throat, lips
  • blurred vision
  • change in the amount of urine passed
  • difficulty swallowing, severe heartburn or burning, pain in throat
  • pain or difficulty passing urine
  • stomach pain or cramps
  • swelling of feet or ankles
  • vomiting blood or vomit that looks like coffee grounds

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • diarrhea
  • dizziness, drowsiness
  • gas or heartburn
  • headache
  • nausea, vomiting

What should I watch for while taking ibuprofen?

Let your prescriber or health care professional know if your pain continues, do not take with other pain-killers without advice. Do not treat yourself for a fever with ibuprofen for more than 3 days, or for pain for more than 10 days without asking your prescriber or health care professional for advice. You may be covering up a more serious illness.

To reduce unpleasant effects on your throat and stomach, take ibuprofen with a full glass of water and never just before lying down. If you notice black, tarry stools or experience severe stomach pain and vomit blood or what looks like coffee grounds, notify your health care prescriber immediately.

If you are taking medicines that affect the clotting of your blood, such as aspirin or blood thinners such as Coumadin®, talk to your health care provider or prescriber before taking this medicine.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how ibuprofen affects you. Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Do not smoke cigarettes or drink alcohol; these may increase the irritation to your stomach when taking this medicine.

It is especially important not to use ibuprofen during the last 3 months of pregnancy unless specifically directed to do so by your health care provider. Ibuprofen may cause problems in the unborn child or complications during delivery.

If you are going to have surgery, tell your prescriber or health care professional that you are taking ibuprofen. Problems can arise if you need dental work, and in the day to day care of your teeth. Try to avoid damage to your teeth and gums when you brush or floss your teeth.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 °C (59 and 86 °F). Keep container tightly closed. Throw away any unused medicine after the expiration date.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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