Known interactions

Acanthopanax senticosus, Achillea, Achillea millefolium, African Pepper, Ague Tree, Alant, American Scullcap, Anthemis nobilis, Apricot Vine, Awa, Baikal Scullcap, Baikal Skullcap Root, Baldarian, Balm Mint, Bird Pepper, Bloodwort, Blue Pimpernel, Bramhi, Breezee Mist Antifungal, Calendula, Calendula officinalis, Capsicum, Capsicum annuum, Capsicum frutescens, Catmint, Catnep, Catnip, Catrup, Catswort, Centella asiatica, Chamomile, Chili Pepper, Ci Wu Jia, Cinnamon Wood, Common Scullcap, Corona de Cristo, Devil's Bush, Devil's Leaf, Diflucan Injection, Diflucan Oral, Elecampane, Eleuthero, Eleutherococcus senticosus, Elf Dock, Elfwort, Eyebalm, Femizol-M Vaginal Cream, Field Balm, Field Wort, Fluconazole Injection, Fluconazole Oral, Fluoxetine and Olanzapine, Fluoxetine capsules (Sarafem), Fluoxetine Oral Solution, Fluoxetine tablets or capsules, Fluvoxamine, Fungoid Tincture, fluoxetine delayed-release capsules, Garden Heliotrope, Garden Marigold, Genuine chamomile, German Chamomile, Goat's Pod, Gold Bloom, Golden Marigold, Goldenseal, Gotu Kola, Granadilla, Green Arrow, Ground Raspberry, Helmet Flower, Holligold, Hoodwort, Hops, Horse-elder, Horseheal, Houblon, Huang Qin, Humulus lupulus, Hungarian chamomile, Hwanggum, Hydrocotyle asiatica, Indian Pennywort, Intraconazole Injection, Inula helenium, Itraconazole, Itraconazole Oral Solution, Kaletra, Kaletra Solution, Kava, Kava-Kava, Kawa, Ketoconazole Oral, Ketoconazole Shampoo, Ketoconazole Topical, Kew, L-tryptophan, Lemon Balm, Leonurus cardiaca, Lion's Ear, Lion's Tail, Lopinavir and Ritonavir, Lopinavir and Ritonavir Oral Solution, Lotrimin AF Aerosol Liquid, Lotrimin AF Aerosol Powder, Lupulin, Luvox, Mad-Dog Weed, Marsh Penny, Marybud, Matricaria chamomilla, Maypop, MEL, Melatonin, Melissa, Melissa officinalis, Mexican Chillies, Micatin, Micatin Aerosol Liquid, Micatin Aerosol Powder, Miconazole Aerosol Powder/Liquid, Miconazole Topical, Miconazole Vaginal Cream, Miconazole Vaginal Suppository, Milfoil, MLT, Monistat 3 Vaginal Cream, Monistat 7 Vaginal Cream, Monistat Vaginal Cream, Monistat-7 Vaginal Suppository, Monistat-Derm, Motherwort, Mycobutin, N-acetyl-5-methoxytryptamine, Nepeta cataria, Nettle, Nettle Tops, Nizoral Cream, Nizoral Shampoo, Nizoral Tablets, Norvir, Norvir Oral Solution, Nosebleed Plant, Ogon, Orangeroot, Paprika, Paroxetine, Paroxetine Oral Suspension, Passiflora incarnata, Passion Flower, Passion Vine, Paxil, Paxil CR, Paxil Suspension, Piper methysticum, Pot Marigold, Prozac, Prozac Oral Solution, Prozac Weekly, Pushkarmoola, Quaker Bonnet, Red Pepper, Rifabutin, Rifadin, Rifadin Injection, Rifampin, Rifampin Injection, Rimactane, Ritonavir, Ritonavir Oral Solution, Roman Chamomile, Roman Nettle, Russian Root, Saloop, Sarafem, Sassafras, Sassafras albidum, Sassafras officinale, Saxifras, Scabwort, Scullcap, Scute, Scutellaria baicalensis, Scutellaria lateriflora, Sertraline, Sertraline Oral Solution, Shigoka, Siberian Ginseng, Skullcap, Sporanox, Sporanox Injection, Sporanox Oral Solution, Staunch Weed, Stinging Nettle, Sweet Balm, Symbyax, Tabasco Pepper, Taiga, Tetterine, Thorny Pepperbush, Thousand-Leaf, Throw-wort, Tonga, Touch-Me-Not, Tryptophan, Urtica species, Valerian, Valeriana officinalis, Valeriana sambucifolia, Valeriana wallichi, Valeriane, Velvet Dock, Water Lemon, Wild Pepper, Wild Sunflower, Wogon, Wound Wort, Yagona, Yarrow, Yarroway, Yellow Starwort, Yellowroot, Zanzibar Pepper, Zeasorb-AF, Zeasorb-AF Aerosol Powder, Zoloft, Zoloft Oral Solution.

Application of Ambien

Brand Name(s): Ambien

Generic Name Zolpidem

What are zolpidem tablets?

ZOLPIDEM (Ambien®) is a sedative-type drug that helps to relieve insomnia (sleeplessness). Trouble falling asleep, waking up too early in the morning, or waking up too often during the night are symptoms of insomnia. Zolpidem helps treat these problems with sleep, and is usually used for no longer than a few days to a few weeks. Sleep medicines should not be taken for long periods of time, except on your prescriber's advice. Do not share your medicine with anyone else. Generic zolpidem tablets are not yet available.

What should my health care professional know before I take zolpidem?

They need to know if you have any of these conditions:

  • frequently drink alcohol
  • depression
  • history of a drug abuse problem
  • liver disease
  • lung or respiratory disease (breathing difficulties, like emphysema or sleep apnea)
  • an unusual or allergic reaction to zolpidem, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I take this medicine?

Take zolpidem tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. It is better to take zolpidem on an empty stomach (without food) and only when you are ready for bed. Do not take your medicine more often than directed. Do not share your medicine with anyone else.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

Elderly patients over age 65 years may have a stronger reaction to this medicine and need smaller doses.

What if I miss a dose?

This does not apply. Zolpidem should only be taken immediately before going to sleep. Do not take double or extra doses.

What drug(s) may interact with zolpidem?

  • bupropion
  • caffeine
  • flumazenil
  • certain antidepressants, like citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, or venlafaxine
  • medications for fungal infections, like ketoconazole, fluconazole, or itraconazole
  • some medicines used to treat HIV infection or AIDS, like ritonavir
  • St. John's wort

Certain medications may cause additive drowsiness or decrease alertness with zolpidem:

  • alcohol
  • allergy, cough, or cold medications (antihistamines)
  • kava kava
  • melatonin
  • medicines for anxiety
  • medicines for pain
  • medicines for treating mental problems
  • melatonin
  • other sedatives given for sleep
  • some medicines for Parkinson' s disease or other movement disorders
  • valerian

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking zolpidem?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • confusion
  • depressed mood
  • hallucinations (seeing, hearing, or feeling things that are not really there)
  • lightheadedness, fainting spells or falls
  • slurred speech or difficulty with coordination
  • vision changes
  • restlessness, excitability, or feelings of agitation

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • diarrhea
  • dizziness, or daytime drowsiness, sometimes called a "hangover" effect
  • headache
  • strange dreams
  • slight stomach upset

What should I watch for while taking zolpidem?

Visit your prescriber or health care professional for regular checks on your progress. In most cases zolpidem should only be taken for a few days and for not longer than 1 or 2 weeks. Keep a regular sleep schedule by going to bed at about the same time nightly. Avoid caffeine-containing drinks in the evening hours, as caffeine can cause trouble with falling asleep. Consult your prescriber or health care professional if you still have difficulty in sleeping.

Sleep medicines sometimes cause a type of memory loss, in which the person may not remember what has happened in the several hours after taking the medication. This type of memory loss is usually not a problem since zolpidem is taken right before bedtime. Be sure to talk to your doctor if you think you are having memory problems while on this medication.

If you have been taking zolpidem for several weeks and suddenly stop taking it, you may get unpleasant withdrawal symptoms. Your prescriber or health care professional may want to gradually reduce the dose. Do not stop taking zolpidem on your own. Always follow your prescriber's advice.

After you stop taking your zolpidem prescription, you may notice some trouble with falling asleep. This is sometimes called "rebound insomnia". Do not get discouraged, because this problem usually goes away on its own after 1 or 2 nights.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how zolpidem affects you. To reduce dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can increase possible unpleasant effects. Do not drink alcoholic drinks while taking medications to help you sleep.

If you are going to have surgery, tell your prescriber or health care professional that you are taking zolpidem.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at controlled room temperature, 20 and 25 °C (68 and 77 °F). Throw away any unused medicine after the expiration date.

(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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