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Information about Inapsine

Brand Name(s): Inapsine

Generic Name Droperidol Injection

What is droperidol injection?

DROPERIDOL (Inapsine®) is used to prevent nausea and vomiting associated with medicines given during surgery or other procedures. Generic droperidol injections are available.

What should my health care professional know before I receive droperidol?

They need to know if you have any of these conditions:

  • if you frequently drink alcohol-containing beverages
  • heart disease, including heart failure
  • irregular heart beats or slow heart rate
  • liver disease
  • low blood pressure
  • kidney disease
  • Parkinson's disease
  • seizures (convulsions)
  • an unusual or allergic reaction to droperidol, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Droperidol is for injection into a muscle or for slow injection into a vein. Droperidol is only given by health care professionals in a controlled environment, such as a hospital or clinic.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. Use in children less than 2 years of age is not recommended.

What if I miss a dose?

This does not apply.

What drug(s) may interact with droperidol?

Droperidol should only be given with extreme caution if you are receiving any of these drugs:

  • arsenic trioxide
  • astemizole
  • bepridil
  • certain antibiotics (such as clarithromycin, erythromycin, gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sparfloxacin)
  • cisapride
  • cisplatin
  • foscarnet
  • levodopa, entacapone or other medicines for Parkinson's disease
  • levomethadyl
  • medicines for asthma or breathing difficulties (such as formoterol or salmeterol)
  • medicines for depression
  • some medicines for treating mental disturbances or severe mood problems (examples: chlorpromazine, pimozide, thioridazine, ziprasidone and many others)
  • medicines to control heart rhythm (examples: amiodarone, digoxin, disopyramide, dofetilide, flecainide, procainamide, quinidine, sotalol)
  • probucol
  • terfenadine
  • water pills (diuretics)

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from receiving droperidol?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • fast or irregular heartbeat (palpitations)
  • fainting spells or dizziness that won't go away
  • hallucinations
  • movement difficulties
  • muscle spasms or stiffness
  • restlessness or agitation, nervousness
  • rolling or rotating movement of the eyes
  • slow or difficult breathing
  • sweating

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • chills
  • dizziness
  • drowsiness
  • facial flushing
  • involuntary muscle movements
  • nightmares
  • trembling

What should I watch for while taking droperidol?

You will be closely monitored following administration of droperidol. You may feel drowsy or dizzy after receiving droperidol. Do not drive, operate machinery, or perform other tasks that require concentration. Alcohol can increase drowsiness or dizziness; avoid alcoholic drinks.

Where can I keep my medicine?

This does not apply. You will only receive this medicine in a hospital or clinic.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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