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Known interactions

No interactions found.

Description of Lamprene

Brand Name(s): Lamprene

Generic Name Clofazimine

What are clofazimine capsules?

CLOFAZIMINE (Lamprene®) is an antiinfective medicine. It kills a certain kind of bacteria that causes leprosy (Hansen's disease). Clofazimine also reduces inflammation caused by the disease. Generic clofazimine capsules are not yet available.

What should my health care professional know before I take clofazimine?

They need to know if you have any of these conditions:

  • bowel problems
  • contact lens wearer
  • diarrhea
  • stomach problems, pain or bleeding
  • an unusual reaction to clofazimine, other medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I take this medicine?

Take clofazimine capsules by mouth. Follow the directions on the prescription label. Swallow capsules whole with a full glass of water. It is best to take clofazimine with food. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. This can take up to three years. Do not stop taking except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with clofazimine?

  • dapsone

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking clofazimine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • black, tarry stools
  • dark yellow or brown urine
  • depression
  • dry, burning or itching eyes
  • stomach pain
  • yellowing of the eyes or skin
  • unusual tiredness or weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • diarrhea
  • dry, scaly skin
  • increased sensitivity to the sun or ultraviolet light
  • nausea, vomiting
  • pink to brownish-black color of skin, urine, tears, saliva, perspiration or stools
  • skin rash, itching

What should I watch for while taking clofazimine?

Contact your prescriber or health care professional if you get severe stomach pain or diarrhea, or if you get black, tarry stools; do not treat yourself.

This medicine can color your skin, nails, and hair from pink to brownish-black. This color will last for as long as you take clofazimine and is not a cause for alarm. Talk to your prescriber or health care professional about this if it causes you concern or makes you feel depressed. Clofazimine can also color soft contact lens.

If you get dry and scaly skin, you can relieve it by applying oil.

Keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or sun tanning beds or booths.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature below 30 °C (86 °F). Protect from moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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