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Known interactions

No interactions found.

Application of Amlexanox paste

Brand Name(s): Aphthasol

Generic Name Amlexanox

What is amlexanox paste?

AMLEXANOX (Aphthasol®) is a topical paste that is applied to an aphthous ulcer, also known as a canker sore. Amlexanox increases healing and decreases pain related to the ulcer. This medicine should only be used in patients who have no problems with their immune system. Use this medication for the treatment of aphthous ulcers of the mouth only. Do not use for ulcers of the eye or any other area of the body. Generic amlexanox oral paste is not available.

What should my health professional know before I receive amlexanox?

They need to know if you have any of these conditions:

  • any condition that may decrease your immune status such as cancer or HIV
  • receiving chemotherapy or radiation therapy
  • an unusual or allergic reaction to amlexanox, benzyl alcohol, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I take this medicine?

Amlexanox is applied to aphthous ulcers (canker sores) of the mouth only; do not apply to ulcers in eyes or other areas. Wash eyes promptly with clear running water if they should come into contact with the amlexanox paste. Begin applying the paste as soon as possible after noticing the symptoms of an aphthous ulcer. Brush your teeth and then apply amlexanox, usually after breakfast, lunch, dinner and at bedtime. Wash hands before and immediately after applying amlexanox oral paste. Follow the directions on the prescription label. Squeeze a dab of paste approximately 1/4 inch (1/2 cm) onto a clean, moistened finger tip. Dry the ulcer by patting gently with a dry, clean cloth. Dab the correct amount of paste onto each ulcer in the mouth using gentle pressure. Use the paste until the ulcer heals or as directed.

What if I miss a dose?

Apply the paste as soon as possible if you miss a dose, unless it is time for a routine application. Do not double up on doses. Do not apply more than 4 times per day.

What drug(s) may interact with amlexanox?

There are no reports of medicines that interact with amlexanox.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from receiving amlexanox?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • diarrhea
  • inflamed areas of mouth
  • nausea
  • rash

Side effects that usually do not require immediate attention (report to your prescriber or health care professional if they continue or become bothersome):

  • burning or stinging of ulcer when paste is applied
  • transient pain at site of ulcer

What should I watch for while taking amlexanox?

Watch for new inflamed areas of the mouth or a rash. To prevent spreading the aphthous ulcers to new areas of the mouth, wash your hands after every application of paste. Discontinue use and contact your physician or dentist if inflammation of mouth or rash occur.

Watch for healing of ulcer and a decrease in pain. If these do not occur within 10 days of treatment, contact physician or dentist.

Where can I keep my medicine?

Keep this medicine out of the reach of children.

Store amlexanox paste in the original tube at 15 and 30 °C (59 and 86 °F). Throw away any unused medicine after the expiration date.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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