Known interactions

Acular, Acular LS, Advil, Advil Cold & Sinus, Advil Flu & Body Ache, Advil Liqui-Gels, Advil Migraine, Aleve, Amber Touch-and-Heal, Anaprox, Anaprox DS, Ansaid, Arthrotec, Carbex, Carvedilol, Cataflam, Celexa, Celexa Solution, Children's Advil, Children's Advil chewable, Children's Motrin, Children's Motrin chewable, Cimetidine, Cimetidine Injection, Cimetidine Liquid, Citalopram, Citalopram Oral Solution, Citalopram orally-disintegrating tablets, Clinoril, Combunox, Coreg, Cyproheptadine, Cyproheptadine Syrup, citalopram orally-disintegrating tablets, Dalteparin Injection, Daypro, Diclofenac, Diclofenac and Misoprostol, Diclofenac Ophthalmic, Diclofenac Potassium, Diclofenac Topical, Diclofenac XR, Dristan Sinus, EC-Naprosyn, Eldepryl, Enoxaparin Injection, Etodolac, Etodolac ER, Feldene, Fenoprofen, Fluoxetine and Olanzapine, Fluoxetine capsules (Sarafem), Fluoxetine Oral Solution, Fluoxetine tablets or capsules, Flurbiprofen Ophthalmic Drops, Flurbiprofen Oral, Fragmin, fluoxetine delayed-release capsules, Genpril, Haltran, Hardhay, Heparin Injection, Hydrocodone and Ibuprofen, Hypericum, Hypericum perforatum, Ibuprofen, Ibuprofen and Pseudoephedrine Suspension, Ibuprofen and Pseuodoephedrine, Ibuprofen Chewable Tablets, Ibuprofen Oral Drops, Ibuprofen Suspension, Ibuprofen; Oxycodone tablets, Inderal, Inderal IV, Indocin, Indocin IV, Indocin SR, Indocin Suppositories, Indocin Suspension, Indomethacin, Indomethacin Injection, Indomethacin SR, Indomethacin Suppositories, Indomethacin Suspension, Infants' Advil, Infants' Motrin, Innohep, Isocarboxazid, Junior Strength Advil, Junior Strength Motrin, Ketoprofen, Ketorolac Injection, Ketorolac Ophthalmic Drops, Ketorolac Oral, Klamath Weed, Lansoprazole and Naproxen, Linezolid, Linezolid Injection, Linezolid Oral Suspension, Lodine, Lodine XL, Lopressor, Lopressor HCT, Lopressor Injection, Lovenox, Marplan, Meclofenamate, Meclomen, Mefenamic Acid, Meloxicam, Meloxicam Suspension, Menadol, Meridia, Metoprolol and Hydrochlorothiazide, Metoprolol ER, Metoprolol Injection, Metoprolol Oral, Midol Maximum Strength Cramp Formula, Millepertuis, Mobic, Mobic Suspension, Motrin, Motrin Children's Cold Suspension, Motrin IB, Motrin Jr Strength, Motrin Migrain Pain, Motrin Sinus Headache, Nabumetone, Nalfon, Naprelan, Naprosyn, Naprosyn Suspension, Naproxen, Naproxen Oral Suspension, Nardil, Nuprin, Ocufen, Orudis, Oruvail, Oxaprozin, Parnate, Paroxetine, Paroxetine Oral Suspension, Paxil, Paxil CR, Paxil Suspension, PediaCare Fever, PediaCare Fever Suspension, Pediatric Advil Drops, Periactin, Periactin Syrup, Phenelzine, Piroxicam, Ponstel, Prevacid NapraPAC, Propranolol, Propranolol Injection, Propranolol Oral Solution, Prozac, Prozac Oral Solution, Prozac Weekly, Relafen, Reprexain, Rosin Rose, Rufen, Sarafem, Selegiline, Sertraline, Sertraline Oral Solution, Sibutramine, SJW, Solaraze, St. John's Wort, Sulindac, Symbyax, Tagamet, Tagamet HB, Tagamet Injection, Tagamet Liquid, Tinzaparin, Tipton Weed, Tolectin, Tolectin DS, Tolmetin, Toprol XL, Toradol, Toradol Injection, Tramadol, Tramadol and Acetaminophen, Tranylcypromine, Ultracet, Ultram, Vicoprofen, Voltaren, Voltaren Ophthalmic, Voltaren XR, Zoloft, Zoloft Oral Solution, Zyvox, Zyvox Injection, Zyvox Suspension.

Description of Lexapro

Brand Name(s): Lexapro

Generic Name Escitalopram

What are escitalopram tablets?

ESCITALOPRAM (Lexapro™) is a medicine for depression and other related problems. You may have to take escitalopram for up to 4 weeks or longer before you begin to feel better. Generic escitalopram tablets are not yet available.

What should my health care professional know before I take escitalopram?

They need to know if you have any of these conditions:

  • diabetes
  • heart disease
  • kidney disease
  • liver disease
  • mania
  • receive electroconvulsive therapy
  • seizures (convulsions)
  • suicidal thoughts or previous suicidal attempts
  • an unusual or allergic reaction to escitalopram, the related drug citalopram, other medicines, foods, dyes, or preservatives
  • pregnant or trying to become pregnant
  • breast-feeding

How should I take this medicine?

Take escitalopram tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Escitalopram can be taken with or without food. If escitalopram upsets your stomach, taking it with food may help. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your prescriber or health care professional's advice.

What if I miss a dose?

If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Follow your prescriber or health care professional's advice on missed doses.

What drug(s) may interact with escitalopram?

Do not take escitalopram with any of the following medications:

  • cisapride
  • citalopram
  • medicines called MAO inhibitors such as phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), selegiline (Eldepryl®)

Escitalopram may also interact with the following medications:

  • alosetron
  • alprazolam
  • amphetamine
  • aspirin or nonsteroidal antiinflammatory drugs (NSAIDs) such as ibuprofen or naproxen
  • buspirone
  • carbamazepine
  • certain diet drugs (dexfenfluramine, fenfluramine, phentermine, sibutramine)
  • clarithromycin
  • cimetidine
  • cyproheptadine
  • dexamethasone
  • dextromethorphan
  • dextroamphetamine
  • diazepam
  • diltiazem
  • erythromycin
  • ethosuximide
  • furazolidone
  • grapefruit juice
  • itraconazole
  • kava kava
  • ketoconazole
  • linezolid
  • lithium
  • medicines that treat depression or other mood problems
  • medicines that treat HIV infection or AIDS
  • migraine headache medicines (almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan)
  • medicines for psychosis or severe mood problems
  • methadone
  • modafinil
  • nefazodone
  • phenobarbital
  • phenytoin
  • prescription pain relievers (codeine, hydrocodone, meperidine, morphine, tramadol, oxycodone)
  • primidone
  • procarbazine
  • quinine
  • rifabutin
  • rifampin
  • St. John's Wort
  • troglitazone
  • tryptophan
  • valerian
  • verapamil
  • voriconazole
  • warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines. Also tell your prescriber or health care professional if you are a frequent user of grapefruit juice, drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking escitalopram?

Side effects that you should report to your prescriber or health care professional as soon as possible:

Rare or uncommon:

  • confusion
  • dizziness or lightheadedness
  • skin rash, itching (hives)
  • fast talking and excited feelings or actions that are out of control
  • suicidal thoughts
  • vomiting

More common:

  • agitation, anxiety, or restlessness, especially in the first week of treatment or when doses are changed

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • blurred vision
  • diarrhea
  • difficulty sleeping
  • drowsiness
  • dry mouth
  • fever
  • frequent urination
  • headache
  • indigestion, nausea
  • increased or decreased appetite
  • increased sweating
  • sexual difficulties (decreased sexual ability or desire)
  • taste alterations
  • tremor (shaking)
  • weight changes

What should I watch for while taking escitalopram?

Visit your prescriber or health care professional for regular checks on your progress. Continue to take your tablets even if you do not immediately feel better. It can take 1—2 weeks or longer before you feel the first effects of escitalopram.

Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of antidepressant treatment or after a change in dose, call your health care professional.

If you have been taking escitalopram regularly for some time, do not suddenly stop taking it. You must gradually reduce the dose, or your symptoms may get worse. Ask your prescriber or health care professional for advice.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how escitalopram affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of escitalopram. Avoid alcoholic drinks.

Do not treat yourself for coughs, colds, or allergies without asking your prescriber or health care professional for advice. Some ingredients can increase possible side effects.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.

If you are going to have surgery, tell your prescriber or health care professional that you are taking escitalopram.

Where can I keep my medicine?

Keep out of reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 °C (59 and 86 °F). Throw away any unused medicine after the expiration date.

(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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