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Known interactions

No interactions found.

Information about Loteprednol

Brand Name(s): Alrex, Lotemax

Generic Name Loteprednol

What is loteprednol eye suspension?

LOTEPREDNOL (Lotemax™ or Alrex™) is applied to the eye. Loteprednol decreases swelling, redness, or inflammation of the eye which may occur following eye surgery or with other eye conditions (such as conjunctivitis, keratitis, uveitis, and iritis). Generic loteprednol eye suspension is not available.

What should my health care professional know before I use loteprednol?

They need to know if you have any of these conditions:

  • if you wear contact lenses
  • certain eye diseases that cause the cornea to get thin
  • fungal or yeast infection of the eye
  • herpes or other viral infection of the eye
  • any other infection of the eye
  • if you have chickenpox or have been exposed to chickenpox
  • glaucoma
  • an unusual or allergic reaction to loteprednol, glycerin, benzalkonium chloride, other corticosteroids, medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

If you are going to have eye surgery, tell your prescriber or health care professional that you are taking loteprednol.

How should I use this medicine?

Loteprednol eye suspension is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Shake very well (vigorously) before using. Wash your hands before and after use. Tilt your head back slightly, and then pull your lower eyelid down with your index finger to form a pouch. Do not to touch the tip of the dropper to your eye, fingertips, or other surface. Squeeze the prescribed number of drops into the eye pouch. Let go of the eyelid and gently close the eye for a few moments to spread the drops. Do not blink. Keep the eyes closed and apply gentle pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye. If you think you did not get the drop of medicine into your eye, use another drop. Otherwise, do not use the medicine more often than directed. Do not stop using loteprednol earlier than directed by your prescriber. If you are a contact lens wearer, ask your prescriber or health care professional when you can use your lenses again.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What drug(s) may interact with loteprednol?

No interactions with other medicines have been reported.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from using loteprednol?

If loteprednol is used for long periods of time, serious side effects other than those listed below may develop. Report any other unusual effects to your prescriber or health care professional as soon as you can.

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • blurred vision, or a change in vision
  • eye pain or discharge
  • eye infection
  • increased redness and swelling of the eyes
  • sensitivity of the eye to sunlight
  • other unusual change in your eye condition

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • dry, watery, itchy, or irritated eyes
  • headache
  • redness of the eye or inner part of the eyelid
  • runny nose or sore throat
  • temporary blurring of vision
  • the feeling that something is in your eye
  • swelling of the membrane covering the white part of the eye

What should I watch for while taking loteprednol eye suspension?

Check with your prescriber or health care professional if your condition does not improve, or if it gets worse. If your eye condition does not improve after two days, contact your physician. Tell your prescriber or health care professional if you are exposed to anyone with chickenpox.

If you are a contact lens wearer, ask your prescriber or health care professional when you can use your lenses again. In general, you should not wear contact lenses if you are using Lotemax™, the 0.5% loteprednol suspension. If your doctor prescribed Alrex™, the 0.2% loteprednol suspension, you should not wear contact lenses at all if your eyes are red. If your eyes are not red, you should remove the contact lenses while administering Alrex™ (loteprednol 0.2%) and wait at least 10 minutes before putting your contact lenses back on.

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 °C (59 and 77 °F); do not freeze. Throw away any unused medicine after the expiration date.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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