Known interactions

Actonel with calcium, Adriamycin, AK-Pred, Alamag, Alamag Suspension, Alenic Alka, Almora, AlternaGEL, AlternaGEL Liquid, Alu-Cap, Alu-Tab, Aludrox, Aluminum and Magnesium Hydroxide, Aluminum and Magnesium Hydroxide Oral Suspension, Aluminum Hydroxide, Aluminum Hydroxide and Magnesium Trisilicate, Aluminum Hydroxide Oral Liquid, Aluminum Hydroxide, Magnesium Carbonate Chewables, Aluminum Hydroxide, Magnesium Carbonate Oral Suspension, Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone, Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone oral suspension, Amiodarone Injection, Amiodarone Oral, Amitone, Amphojel, Amphojel Suspension, Ara-C, Betapace, Betapace AF, Bretylium, Bretylium Tosylate, Bumetanide, Bumetanide Injection, Bumex, Bumex Injection, Cal-Citrate, Calcium Acetate, Calcium Acetate Capsules or Gelcaps, Calcium Carbonate Tablets, Calcium Citrate, Calcium chloride, Calcium disodium versenate, Calcium Gluconate, Calcium Lactate, Calcium Salts, Calcium Salts injection, Caltrate 600, Carafate, Carafate Oral Suspension, Cardioquin, Citracal, Citracal Liquitabs, Citrus Calcium, Cordarone, Cordarone Injection, Coumadin, Coumadin Injection, CTX, Cyclophosphamide, Cyclophosphamide Injection, Cytarabine, Cytosar-U, Cytoxan, Cytoxan Injection, Daunorubicin Liposomal Injection, DaunoXome, DDI, Demadex Injection, Demadex Oral, Di-Gel, Dialume, Dicarbosil, Didanosine, Didanosine Delayed Release Capsule, Didanosine Pediatric Oral Solution, Didanosine Powder for Oral Solution, Disopyramide, Doxorubicin, Econopred, Econopred Plus, Edecrin, Equilet, Ethacrynic Acid, Fe-Tinic, Ferrex 150, Foscarnet Sodium Injection, Foscavir, Furosemide, Furosemide Injection, Furosemide Oral Solution, Gaviscon, Gaviscon Chewable, Gaviscon Chewable Tablets, Inflamase Forte, Inflamase Mild, Iosopan, Jantoven, Lasix, Lasix Injection, Lasix Oral Solution, Maalox, Maalox Suspension, Mag-Ox, Magaldrate, Magnalox, Magnalox Suspension, Magnesium Gluconate, Magnesium Hydroxide, Magnesium Hydroxide Chewable Tablets, Magnesium Oxide, Magnesium Sulfate Injection, Magnox Suspension, Magonate, Magtrate, Mallamint, Maox, Mexiletine, Mexitil, Milk of Magnesia, Milk of Magnesia-Concentrated, Mintox Suspension, Mitoxantrone, Mylanta, Mylanta Oral Suspension, Mylanta tablets, Neosar, Niferex, Niferex 150, Norpace, Norpace CR, Novantrone, Nu-Iron, Nu-Iron-150, Oncovin, Orapred, Pacerone, Pediapred, Phillips Milk of Magnesia, Phillips' Chewable, PhosLo, Phoslo Capsules, Phoslo Gelcaps, Polysaccharide Iron Complex, Polysaccharide Iron Complex Elixir, Posture, Pred Forte, Pred Mild, Prednisolone Injection, Prednisolone Liquid, Prednisolone Ophthalmic, Prednisolone Tablets, Prelone, Procainamide ER, Procainamide Injection, Procainamide Oral, Procan SR, Procanbid, Pronestyl, Pronestyl Injection, Pronestyl-SR, Quinaglute Dura-Tabs, Quinidex Extendtabs, Quinidine, Quinidine Extended-Release, Quinidine Injection, Quinora, Riopan, Risedronate with calcium carbonate, Rubex, Rulox, Sotalol, Sucralfate, Sucralfate Oral Suspension, Titralac, Torsemide Injection, Torsemide Oral, Tricalcium Phosphate, Tums, Uro-Mag, Videx, Videx EC, Videx Pediatric Oral Solution, Videx Powder for Oral Solution, Vincasar, Vincristine, Warfarin, Warfarin injection.

Information about Ofloxacin Injection

Brand Name(s): Floxin IV

Generic Name Ofloxacin Injection

What is ofloxacin injection?

OFLOXACIN (Floxin®) is an antibiotic. Ofloxacin kills certain bacteria or stops their growth. It treats urinary tract, prostate, skin, urinary and respiratory tract infections, as well as certain sexually transmitted diseases. Generic ofloxacin injections are not yet available.

What should my health care professional know before I receive ofloxacin?

They need to know if you have any of these conditions:

  • arteriosclerosis
  • dehydration
  • heart disease
  • kidney disease
  • liver disease
  • long exposure to sunlight (working outdoors)
  • seizures (convulsions)
  • stomach problems (especially colitis)
  • stroke
  • tendon or joint pain
  • other chronic conditions
  • an unusual or allergic reaction to fluoroquinolone antibiotics, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Ofloxacin injection is for infusion into a vein. Follow the directions on the prescription label. Use your doses at regular intervals. Do not use your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop using except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What drug(s) may interact with ofloxacin?

  • arsenic trioxide
  • astemizole
  • bepridil
  • certain heart medications for irregular rhythm (e.g., amiodarone, disopyramide, dofetilide, flecainide, ibutilide, quinidine, procainamide, sotalol)
  • certain medications for depression or other mental problems (e.g., tricyclic antidepressants, amoxapine, maprotiline, phenothiazines, haloperidol, pimozide, risperidone, sertindole, and ziprasidone)
  • cisapride
  • clarithromycin
  • cyclobenzaprine
  • cyclosporine
  • dolasetron
  • droperidol
  • erythromycin
  • levomethadyl
  • medicines for diabetes
  • NSAIDs such as Advil®, Aleve®, ibuprofen, Motrin®, naproxen
  • pentamidine
  • probucol
  • terfenadine
  • theophylline
  • troleandomycin
  • warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from receiving ofloxacin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • difficulty breathing
  • irregular heartbeat, palpitations or chest pain
  • joint, muscle or tendon pain
  • pain, swelling and irritation at the injection site
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • severe or watery diarrhea
  • skin rash, itching
  • swelling of the face or neck
  • vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • diarrhea
  • difficulty sleeping
  • dizziness, drowsiness
  • headache
  • nausea

What should I watch for while taking ofloxacin?

Tell your prescriber or health care professional if your symptoms do not improve in 2 to 3 days.

If you are a diabetic using insulin or oral hypoglycemics (like glyburide) monitor your blood glucose carefully. If you get an unusual reaction stop using ofloxacin at once and call your prescriber or health care professional for advice.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how ofloxacin affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient.

Drink several glasses of water a day. Cut down on drinks that contain caffeine.

Keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or sun tanning beds or booths.

If you notice pain or soreness of a tendon or around a joint, let your healthcare provider know immediately. You must rest and stop exercise until your healthcare provider says it is okay to start again.

If you are going to have surgery, tell your prescriber or health care professional that you are using ofloxacin.

Where can I keep my medicine?

Keep out of the reach of children.

Follow manufacturer's advice on the storage of diluted solutions; do not refreeze. Throw away if solution becomes discolored or particulate matter is present. Throw away any unused injection solution after the expiration date.

(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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