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Known interactions

No interactions found.

Information about T-Gen Rectal Suppositories

Brand Name(s): T-Gen Rectal Suppositories, Tebamide Rectal Suppositories, Tigan Rectal Suppositories, Trinazide Rectal Suppositories

Generic Name Trimethobenzamide Rectal Suppositories

What is trimethobenzamide suppositories?

TRIMETHOBENZAMIDE (Tebamide®, T-Gen®, Tigan®, Trimazide®) helps to control nausea and vomiting. Generic trimethobenzamide suppositories are available.

What should my health care professional know before I receive trimethobenzamide?

They need to know if you have any of these conditions:

  • dehydration
  • recent viral illness
  • stomach or intestinal problems
  • an unusual or allergic reaction to trimethobenzamide, benzocaine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Trimethobenzamide suppositories are put into the rectum. Do not take by mouth. Wash your hands. Take off the wrapping. Wet the tip of the suppository with water to make it easier to use. Lie on your side and raise your knee to your chest. Using your finger, gently push the suppository into the rectum. Hold it in place for a few minutes. Wash your hands. Do not use your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. These suppositories are not for use in premature or newborn infants.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What drug(s) may interact with trimethobenzamide?

  • alcohol
  • atropine, belladonna alkaloids, hyoscyamine, scopolamine
  • medicines for sleep or anxiety
  • medicines for pain
  • phenobarbital or other barbiturates

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from receiving trimethobenzamide?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • difficulty breathing, wheezing, shortness of breath
  • tightness in the chest
  • sore throat or fever
  • shakiness or tremors
  • seizures
  • severe or continuing vomiting
  • skin rash
  • swelling of the face, tongue, throat, hands and feet
  • yellowing of the eyes or skin
  • unusual tiredness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • blurred vision
  • diarrhea
  • dizziness
  • drowsiness
  • headache
  • muscle cramps

What should I watch for while taking trimethobenzamide?

If your condition worsens after taking trimethobenzamide, contact your health care professional immediately.

Trimethobenzamide may cause blurred vision, dizziness, and drowsiness. Driving or operating machinery, or performing other tasks that require mental alertness requires caution when taking this drug. You should not participate in these activities until you determine how trimethobenzamide affects you.

Do not drink alcohol while taking trimethobenzamide. Alcohol can increase side effects.

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 °C (59 and 86 °F). Keep in a well-closed container. Throw away any unused portion after the expiration date.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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