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Known interactions

A-Spas S/L, Acetaminophen and Butalbital, Activated Charcoal, AK-Chlor, Amobarbital, Amytal, Anaspaz, Antispas Injection, Antispasmodic Elixer, Anturane Capsules, AnturaneTablets, Artane, Artane Elixir, Artane Sequels, Atretol, AtroPen, Atropine Auto-Injection, Atropine Care, Atropine Injection, Atropine Ophthalmic, Atropine Oral, Atropine, Hyoscyamine, Phenobarbital, and Scopolamine Oral, Atropine, Hyoscyamine, Phenobarbital, and Scopolamine Elixir, Atropisol, Axocet, AZT Capsule, AZT Injection, AZT Oral Syrup, AZT tablets, Azidothymidine Capsule, Azidothymidine Injection, Bellacane SR, Belladonna Alkaloids, Ergotamine, and Phenobarbital Tablets, Bellaspas, Bellergal-S, Benemid, Bentyl, Bentyl Injection, Bentyl Syrup, Benztropine Mesylate Injection, Benztropine Mesylate Oral, Bucet, Bumetanide, Bumetanide Injection, Bumex, Bumex Injection, Bupap, Butabarbital, Butabarbital Oral Elixir, Butex Forte, Butisol, Butisol Elixir, Byclomine, Carbamazepine, Carbamazepine ER, Carbamazepine Suspension, Carbatrol, Cephadyn, Cerebyx, Chaparral, CharcoAid, Charcoal, Charcoal capsules, Charcoal Plus, Charcoal powder or oral suspension, CharcoCaps, Chloramphenicol, Chloramphenicol Ear Solution, Chloramphenicol Injection, Chloramphenicol Ophthalmic, Chloramphenicol skin cream, Chlordiazepoxide and Clidinium Bromide, Chloromycetin, Chloromycetin Injection, Chloromycetin Ophthalmic, Chloroptic, Chloroptic S.O.P., Cogentin, Cogentin Injection, Compound S, Compound S Capsule, Compound S Oral Syrup, Coumadin, Coumadin Injection, Creosote bush, Cystospaz, Cystospaz-M, Demadex Injection, Demadex Oral, Di-Spaz, Di-Spaz Injection, Dibent Injection, Dicyclomine, Dicyclomine Injection, Dicyclomine Syrup, Dilantin, Dilantin Infatab, Dilantin Injection, Dilantin Kapseals, Dilantin-125, Dilomine Injection, Ditropan, Ditropan Syrup, Dolgic, Donnamar, Donnatal, Donnatal Elixir, Drospirenone and Ethinyl Estradiol, ED-SPAZ, Edecrin, Epitol, Equetro, Estradiol and Norgestimate, Ethacrynic Acid, Ethotoin, Etonogestrel and ethinyl estradiol vaginal ring, Folergot-DF, Fosphenytoin, Furosemide, Furosemide Injection, Furosemide Oral Solution, Gastrosed, Glycopyrrolate, Glycopyrrolate Injection, Greaswood, Hediondilla, Hyoscyamine, Hyoscyamine Injection, Hyoscyamine Liquid, Hyoscyamine Sublingual Tablets, Hyoscyamine sustained-release, Hyosophen Elixer, INH, INH Oral Syrup, Inderal, Inderal IV, Isoniazid, Isoniazid Injection, Isoniazid Oral Syrup, Isopto Atropine, Isopto Hyoscine, Jantoven, Lamictal, Lamotrigine, Larrea divaricata, Larrea glutinosa, Larrea tridentata, Lasix, Lasix Injection, Lasix Oral Solution, Levsin, Levsin /SL, Levsin Elixir, Levsin Injection, Levsinex Timecaps, Librax, Luminal Sodium, Lunelle, Mebaral, Medroxyprogesterone acetate and Estradiol cypionate injection, Mephobarbital, Methscopolamine, Mycobutin, Mysoline, Mysoline Suspension, Nembutal Elixir, Nembutal Injection, Nembutal Oral, Nembutal Sodium, Neosol, Norflex, Norflex Injection, NuvaRing, Nydrazid, Nydrazid Injection, Or-Tyl Injection, Orphenadrine, Orphenadrine Injection, Ortho-Prefest, Oxcarbazepine, Oxcarbazepine Oral Suspension, Oxybutynin, Oxybutynin Oral Syrup, Oxybutynin Patch, Oxytrol, Pamine, Peganone, Pentobarbital Injection, Pentobarbital Elixir, Pentobarbital Oral, Pentobarbital Suppositories, Phenerbel-S, Phenobarbital, Phenobarbital Elixir, Phenobarbital Injection, Phenytek, Phenytoin, Phenytoin Chewable, Phenytoin Injection, Phenytoin Oral Suspension, Phrenilin Forte, Prefest, Priftin, Primidone, Primidone Oral Suspension, Pro-Banthine, Probalan, Probenecid, Propantheline, Propranolol, Propranolol Injection, Propranolol Oral Solution, Repan CF, Retrovir Capsule, Retrovir Injection, Retrovir Oral Syrup, Retrovir tablets, Rifabutin, Rifadin, Rifadin Injection, Rifampin, Rifampin Injection, Rifapentine, Rimactane, Robinul, Robinul Forte, Robinul Injection, Sal-Tropine, Sarisol No.2, Scopace, Scopolamine Injection, Scopolamine Ophthalmic, Scopolamine Patch, Scopolamine Tablets, Secobarbital, Seconal, Sedapap, Solfoton, Spasmoject Injection, Spastrin, Stinkweed, Sulfinpyrazone Capsules, Sulfinpyrazone Tablets, Symax, Symax Duotabs, Symax SR, Symax-SL, Symax-SR, Tegretol, Tegretol Suspension, Tegretol XR, Tencon, Torsemide Injection, Torsemide Oral, Transderm-Scop, Transdermal scopolamine, Trihexane, Trihexy, Trihexy-2, Trihexy-5, Trihexyphenidyl, Trihexyphenidyl Elixir, Trileptal, Trileptal Suspension, Warfarin, Warfarin injection, Yasmin, ZDV Capsule, ZDV Oral Syrup, ZDV tablets, Zidovudine Capsule, Zidovudine Injection, Zidovudine Oral Syrup, Zidovudine tablets, Food and alcohol.

Using of Tylenol

Brand Name(s): Aspirin Free Anacin, Datril, Genapap, Genebs, Panadol, Tempra, Tylenol, Valorin

Generic Name Acetaminophen

What are acetaminophen tablets, caplets, or chewable tablets?

ACETAMINOPHEN (Tylenol®, Panadol®, Feverall® and many others) is used to relieve mild to moderate pain and reduce fever. It is the preferred treatment for patients with aspirin allergy, ulcers, or clotting (bleeding) disorders. Patients who are taking medicines to treat gout can safely take acetaminophen. There are many generic variations available for adults and children. Tablets can be plain, extended-release, or chewable. Gelcaps or geltabs are also available.

What should my health care professional know before I take acetaminophen?

They need to know if you have any of these conditions:

  • anemia
  • drink more than 3 alcohol-containing drinks per day
  • infection
  • kidney disease
  • liver disease
  • hepatitis
  • phenylketonuria
  • an unusual or allergic reaction to acetaminophen, aspirin, other medicines, foods, dyes or preservatives

How should I take this medicine?

Acetaminophen can be taken as needed for the relief of pain or fever, or may be prescribed by the prescriber or health care professional on a more regular basis. Do not take more often than directed, or more than the recommended dose. Acetaminophen tablets come in several strengths for children and adults. Make sure you are taking or giving the correct dose. Take acetaminophen tablets, caplets or gelcaps by mouth. Follow the directions on the label. Chewable tablets can be chewed before swallowing, crushed and taken with food, or mixed in a drink. Swallow extended-release tablets whole, do not crush or chew. Drink a full glass of water either with or after taking your medicine.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. Do not administer adult acetaminophen preparations to children.

What if I miss a dose?

If your prescriber or health care professional has prescribed a regular schedule and you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with acetaminophen?

  • alcohol
  • medicines for seizures
  • antacids
  • cimetidine
  • medicines for mental problems and psychotic disturbances
  • warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking acetaminophen?

If you take acetaminophen as recommended, serious side effects are uncommon.

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • skin rash or hives
  • unusual bleeding or bruising, pinpoint red spots on the skin
  • difficulty breathing, wheezing
  • bloody or black, tarry stools
  • decrease in amount of urine passed
  • not willing to eat
  • fever or sore throat
  • nausea, vomiting
  • stomach cramps and pain
  • unusual tiredness or weakness
  • yellowing of the skin or eyes

What should I watch for while taking acetaminophen?

Do not treat yourself for pain for more than 10 days (5 days for children) without checking with your prescriber or health care professional. If you are treating a fever, check with your prescriber or health care professional if the fever lasts for more than 3 days.

Report any possible overdose promptly to your prescriber or health care professional as soon as possible. The effects of excessive doses may not be obvious for several days.

Avoid alcoholic drinks if you are taking acetaminophen on a regular basis. Alcohol can increase possible damage to your liver.

Many non-prescription medicines contain acetaminophen as an ingredient. Always read the labels carefully to avoid taking an accidental overdose, which can be dangerous.

Certain acetaminophen products containing the artificial sweetener aspartame (Nutrasweet®).

Acetaminophen can affect the results from some blood-sugar tests used by diabetic patients. Check with your prescriber or health care professional before you change your diet or the dose of your diabetic medicine.

If you are receiving cancer chemotherapy or other immunosuppression medicine, do not take acetaminophen with out checking with your prescriber or health care professional. Acetaminophen may hide the signs of an infection such as fever or pain.

Where can I keep my medicine?

Keep out of reach of children in a container that small children cannot open. Acetaminophen can be dangerous to children. Avoid accidental overdose of acetaminophen as this may result in severe effects and possibly death.

Store at room temperature between 15 and 30 °C (59 and 86 °F). Protect from moisture and light. Throw away any unused medicine after the expiration date.


(Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.)

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