Known interactions between the following drugs: 4-Way Fast Acting, Reserpine

Catecholamines are referred to as "neurotransmitters"--chemicals produced by the body that carry messages to nerve cells located throughout the body. There are several different types of catecholamines and each has a specific effect, such as causing blood pressure to increase or making the heart beat faster. Phenylephrine mimics the effect of the catecholamines and is often used to increase blood pressure that has become dangerously low. Reserpine is used to treat high blood pressure and works by depleting natural catecholamines. However, this may make your body more sensitive to the effects of catecholamines that come from a drug. Because of this potential interaction, your blood pressure may become elevated when phenylephrine and reserpine are used at the same time. If these drugs must be used together, your doctor may want to monitor your blood pressure more frequently and adjust the dose of phenylephrine if needed. Phenylephrine is also an ingredient that is commonly contained in over-the-counter nasal decongestants and other products used to relieve cold and flu symptoms. To avoid potential problems, ask your doctor or pharmacist before using any over-the-counter drugs--including herbal supplements--while you are taking reserpine. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.