1 interaction was found for the drugs you selected.
CIMETIDINE in Tagamet
may interact with CAFFEINE in Cafetrate Suppositories
Cimetidine may reduce the breakdown of caffeine by the liver. If this happens, blood levels of caffeine may be increased and this may cause intolerable or otherwise undesirable side effects. Side effects of excessive caffeine include nervousness, headaches, difficulty sleeping, nausea, and increased heart rate. If you are experiencing problems, it may be necessary to avoid caffeine or reduce the amount consumed. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.
This interaction is poorly documented and is considered minor in severity.