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Known interactions between the following drugs: Calan SR, Zocor

1 interaction was found for the drugs you selected.

SIMVASTATIN in Zocor may interact with VERAPAMIL in Calan SR
Verapamil may block the breakdown of simvastatin by the liver. If this happens, blood levels of simvastatin could be increased. This could cause a serious or potentially life-threatening side effect that involves the destruction of muscle tissue and could lead to kidney failure. Avoid using these drugs together if possible, However, if it is necessary to take verapamil and simvastatin at the same time, you may be advised to watch for symptoms like unexplained muscle pain, tenderness, or weakness. Your doctor may consider adjusting the dose of simvastatin if needed or using an alternative to simvastatin for reducing cholesterol. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.

This interaction is well-documented and is considered moderate in severity.


(Note: Not all drug interactions are known or reported in the literature, and new drug interactions are continually being reported. This information is provided only for your education and for you to discuss with your personal healthcare provider.)

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