1 interaction was found for the drugs you selected.
DILTIAZEM in Cardizem Injection
may interact with ERYTHROMYCIN in Erythromycin Tablets, Capsules, and Extended-Release
Both verapamil and erythromycin are normally broken down by the liver into less active or completely inactive by-products - a process referred to as 'drug metabolism.' When these drugs are used at the same time, the liver's ability to metabolize either drug may be altered. Verapamil may block the breakdown of erythromycin, while erythromycin may block the breakdown of verapamil. As a result, blood levels of verapamil and erythromycin may be increased and this could increase the risk of side effects on the heart. If verapamil and erythromycin are taken at the same time, your doctor may want to closely monitor you to make sure your heart is functioning properly. Ask your healthcare provider about these drugs and this potential interaction as soon as possible.
This interaction is poorly documented and is considered major in severity.
(Note: Not all drug interactions are known or reported in the literature, and new drug interactions are continually being reported. This information is provided only for your education and for you to discuss with your personal healthcare provider.)