Known interactions between the following drugs: Cardizem SR, Lipitor

Diltiazem may block the breakdown of atorvastatin in the body. If this happens, blood levels of atorvastatin could be increased. This could cause a serious or potentially life-threatening side effect that involves the destruction of muscle tissue and could lead to kidney failure. Avoid using these drugs together if possible. However, if it is necessary to take diltiazem and atorvastatin at the same time, you should be advised to watch for symptoms like unexplained muscle pain, tenderness, or weakness. If you are experiencing problems, your doctor may consider using an alternative to atorvastatin for reducing cholesterol. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.