Known interactions between the following drugs: Adapin, Effexor

Venlafaxine may interfere with the breakdown of doxepin in the body. This could increase the blood levels of doxepin leading to increased effectiveness of doxepin but also increased risk for side effects from doxepin. If these two medications are used together, your doctor may want to monitor your response to doxepin more closely and adjust the dose of doxepin if needed, especially when venlafaxine is either started or stopped. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.