1 interaction was found for the drugs you selected.
METRONIDAZOLE in Flagyl ER
may interact with CIMETIDINE in Cimetidine
Cimetidine may block the breakdown of metronidazole by the liver. If this happens, blood levels of metronidazole could be increased and this could increase the risk of side effects. Side effects that commonly occur with the use of metronidazole include nausea and vomitting, loss of appetite, headache, and a metallic taste in the mouth. Other side effects that are less likely to occur include insomnia, drowsiness, depression, and a darkening of the urine. If cimetidine and metronidazole are used at the same time, your doctor may want to monitor you for side effects and adjust the dose of metronidazole, if needed. Your doctor may also consider using an alternative to metronidazole for the treatment of an infection. You may want to ask your healthcare provider about this potential interaction if you think you are having problems.
This interaction is poorly documented and is considered minor in severity.