1 interaction was found for the drugs you selected.
WARFARIN SODIUM in Coumadin
may interact with TRAZODONE in Trazodone
Although the cause of this potential interaction is not clearly understood, trazodone may decrease the anticoagulant effect of warfarin. Warfarin is generally used to prevent your blood from "coagulating" or forming blood clots. When trazodone and warfarin are used at the same time, warfarin may be less effective and this could cause the blood to clot more. If these drugs are taken together, your doctor may want to monitor you closely for signs of a clotting disorder. Blood tests can be used to make sure that you are getting the right amount of warfarin. If you are experiencing problems, it may be necessary to adjust the dose of warfarin. You may want to ask your healthcare provider about this potential interaction if you think you are having problems.
This interaction is poorly documented and is considered moderate in severity.