Known interactions between the following drugs: DHT, Zaroxolyn

Dihydrotachysterol (vitamin D) helps the body absorb calcium from the stomach so that it can be distributed throughout the body. Although it does not appear to have a direct effect on dihydrotachysterol, metolazone may prevent the kidneys from removing excess calcium from the body as they normally would. This may lead to hypercalcemia, the condition that occurs when there is too much calcium in the body. Symptoms of hypercalcemia include a loss of appetite, nausea, increased thirst, fatigue, and muscle weakness. Excessively high levels of calcium may cause an irregular heartbeat and damage to the kidneys. If you are taking dihydrotachysterol and metolazone at the same time, your doctor may want to monitor you closely to make sure that you are not getting too much calcium and discontinue therapy with one or both drugs if necessary. You may want to ask your healthcare provider about this potential interaction if you think you are having problems.