1 interaction was found for the drugs you selected.
Kava-Kava in Kava
may interact with ZOLPIDEM TARTRATE in Ambien
The use of kava is discouraged due to serious side effects that it may cause. In addition, kava contains substances that promote mild sedation. When it is used at the same time as zolpidem, kava may intensify zolpidem's sedative effect. Excessive drowsiness, slowed breathing, loss of muscle control, and even coma may result. Kava should not be used -- especially with zolpidem.
Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.
This interaction is well-documented and is considered moderate in severity.