Known interactions between the following drugs: Amigesic, Maxidex

Salsalate is broken down by the liver and removed from the body in the urine. If this happens too quickly, then potentially less salsalate would be available for the body to use and blood levels could become too low. This could make salsalate less effective. Dexamethasone may cause salsalate to be broken down at a faster rate than normal, and may also increase the elimination of salsalate in the urine. If these drugs are taken together, your doctor may want to monitor you closely when therapy with dexamethasone is either started or stopped. If you are experiencing problems, it may be necessary to adjust the dose of salsalate. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.