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Known interactions between the following drugs: Melatonin, Plavix

1 interaction was found for the drugs you selected.

Melatonin in Melatonin may interact with CLOPIDOGREL in Plavix
Chemicals in melatonin may reduce the stickiness of blood components called platelets. Platelets are partly responsible for forming blood clots that stop bleeding from injuries. When taken together with drugs like clopidogrel that also decrease the blood's ability to clot, supplemental melatonin may increase the risk of dangerous bleeding. Individuals who take both may need more frequent blood tests to make sure that blood is clotting properly. Those who experience problems, may need to stop taking supplemental melatonin until clopidogrel is discontinued. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.

This interaction is poorly documented and is considered moderate in severity.


(Note: Not all drug interactions are known or reported in the literature, and new drug interactions are continually being reported. This information is provided only for your education and for you to discuss with your personal healthcare provider.)

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