1 interaction was found for the drugs you selected.
St. John's Wort in St. John's Wort
may interact with Lorazepam in Ativan
Both lorazepam and St. John's wort relax the central nervous system. When they are used together, the risk of excessive sedation and other side effects may be increased. Oversedation including daytime drowsiness, confusion, disorientation, and uncoordinated movement can occur. Slowed reaction time may make trying to drive hazardous. Low body temperature and the inability to walk are serious side effects that need a doctor's attention. Do not use St. John's wort or any other herbal supplement while you are taking lorazepam. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.
This interaction is poorly documented and is considered moderate in severity.