Known interactions between the following drugs: Bosentan, Vfend Injection

Voriconazole may block the breakdown of bosentan by the liver. As a result, blood levels of bosentan may become elevated and this could increase the risk for side effects such as headache. If these drugs are used together, your doctor may want to monitor you closely when therapy with voriconazole is either started or stopped. If you are experiencing problems, it may be necessary for your doctor to adjust the dose of bosentan. Discuss this potential interaction with your healthcare provider at your next appointment, or sooner if you think you are having problems.